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The International Arbuzovs Prize in the field of organophosphorous chemistry

July 11, 1997, on the eve of the 120th anniversary of academician Alexander Е. Arbuzov, outstanding chemist, the Creator of a new branch of chemistry - chemistry of organophosphorus compounds, President of Tatarstan Mintimer Shaimiev signed a Decree on the establishment of the International Arbuzovs Prize in the field of organophosphorus chemistry.

Laboratory of chemical-biological research

Laboratory of Chemical and Biological Research was founded in 2008 by merging the biological group of the Chemical and Biological Research Laboratory and the biotechnology group of the Laboratory of Phosphorus-Containing Analogues of Natural Compounds.

Head of the Laboratory is Doctor of Chemistry,

Professor Vladimir V. Zobov.

Email: zobov@iopc.ru

Main directions of research

Investigation of the relationship "chemical structure - bioactivity" and features of the mechanism of action of the most active synthesized compounds. The principal possibility of creation of organic- and tissue-specific acetylcholinesterase inhibitors, capable of selective modulation of the transsynaptic transfer of locomotory muscle without destruction of vital functions of breathing, heart, brain, designed for using in medicine for treatment of diseases of musculoskeletal system and others, is demonstrated.
Development of the scientific foundations for obtaining practically valuable low- and high-molecular compounds from plant raw material, including biofuels production. The regularities of complexation and methods of synthesis of water-soluble metal complexes based on fully deetherified pectin were studied, the ability of sodium-iron-cobalt-copper-polygalacturonate and sodium-calcium-iron-polygalacturonate to effectively stimulate erythropoiesis is proved.